The E-Class got a new E320 wagon for 1998, and a more fuel efficient V6 engine alongside of BabySmart airbags, BrakeAssist and a passenger airbag in the front. For 1999, more airbags were added to the E-Class including side curtain airbags. A mild update was made to the E-Class for 2000, with a revised interior and exterior, an updated front end, updated COMMAND system and new wheels.
The AMG trim debuted in 2001, alongside subtle other changes. While no changes were made for 2002, the 2003 model offered a new and available, more powerful V8 engine and quad-zone climate control. The E320 wagon was redesigned for 2004, and the DVD navigation system was updated. In 2005, the E320 CDI was introduced, offering turbo-diesel efficiency. Meanwhile, a 3.5-liter V6 engine debuted, along with updated suspension, new wheels and an updated steering wheel. The major update for 2006 was a new 3.5-liter V6 engine with 268 hp.
For 2007, an updated front end debuted with new lighting, a new sport package and moderate updates to the different trim levels. Aside from an updated AMG package, 2008 yielded no major changes. For 2009, the E-Class got a new audio unit with memory card in the dash, and a six-disc CD changer. Trim level changes marked the major updates for 2010, with a new body style and higher quality interior materials. The addition of a new convertible trim level was the big news for 2011, with coupes getting a new grille and an updated interior and refreshed exterior.
2012 saw all E-Class cars getting updated with more fuel efficient engines, with the E63 wagon returning and available all-wheel-drive and stop-start technology. The E350 Coupe 4Matic and the E400 Hybrid were introduced to the lineup in 2013, with a range of new available options. Minor style updates marked the only big changes crossing over into 2014.